https://bindingofisaacrebirth.gamepedia.com/Binding_of_Isaac:_Rebirth_Wiki
The Binding of Isaac is a dungeoneering shooter that pits the player against a series of encounters with numerous enemies and bosses that attempt to overwhelm and thrill. Isaac, the game’s main character, is tortured by his evil mother, who has locked him in the basement. From here, the player must play as Isaac in order to fight their way through a psychological hellscape of nightmarish creatures (all with some kind of sadistic and creepily biblical reference built into them) in order to make it out of the basement to fight and defeat “Mom”: a collection of monstrous limbs that try to kill Isaac. Along the way, the player earns random power-ups for their avatar that increase stats, allow unique abilities (active or passive), etc. Each completion of the game unlocks new items/power-ups, bosses, and levels (including Heaven and Hell).